What is L-Glutamine?
Glutamine is an amino acid (a building block for proteins), found naturally in the body.
Glutamine is used to counter some of the side effects of medical treatments. For example, it is used for side effects of cancer chemotherapy including diarrhea, pain and swelling inside the mouth (mucositis), nerve pain (neuropathy), and muscle and joint pains caused by the cancer drug Taxol. Glutamine is also used to protect the immune system and digestive system in people undergoing radiochemotherapy for cancer of the esophagus. Additionally, glutamine is used for improving recovery after bone marrow transplant or bowel surgery, increasing well-being in people who have suffered traumatic injuries, and preventing infections in critically ill people.
Some people use glutamine for digestive system conditions such as stomach ulcers, ulcerative colitis, and Chron’s disease. It is also used for depression, moodiness, irritability, anxiety, insomnia, and enhancing exercise performance.
People who have HIV (AIDS) sometimes use glutamine to prevent weight loss (HIV wasting).
Glutamine is also used for attention deficit-hyperactivity disorder (ADHD), a urinary condition called cystinuria, sickle cell anemia, and for alcohol withdrawal support.
Glutamine powder can be ordered through most wholesale drug suppliers. Glutamine for commercial use is made by a fermentation process using bacteria that produce glutamine.
How does it work?
Glutamine is the most abundant free amino acid in the body. Amino acids are the building blocks of protein. Glutamine is produced in the muscles and is distributed by the blood to the organs that need it. Glutamine might help gut function, the immune system, and other essential processes in the body, especially in times of stress. It is also important for providing “fuel” (nitrogen and carbon) to many different cells in the body. Glutamine is needed to make other chemicals in the body such as other amino acids and glucose (sugar).
After surgery or traumatic injury, nitrogen is necessary to repair the wounds and keep the vital organs functioning. About one third of this nitrogen comes from glutamine.
If the body uses more glutamine than the muscles can make (i.e., during times of stress), muscle wasting can occur. This can occur in people with HIV/AIDS. Taking glutamine supplements might keep the glutamine stores up.
Some types of chemotherapy can reduce the levels of glutamine in the body. Glutamine treatment is thought to help prevent chemotherapy-related damage by maintaining the life of the affected tissues.
During an intense workout the body is stressed and your muscles and tendons require more glutamine than the amount supplied by a normal diet.
So, after an intense workout the levels of cellular glutamine can drop by 50% and plasma levels to 30%! This ‘muscle wasting state’ is a gateway for the body to use your muscle for energy rather than carbohydrates where glutamine can prevent this from happening.
If you goal is to build muscle, boost metabolism, improve recovery or increase athletic performance then according to the research L-glutamine is a must-have supplement.
Supplementing with L-glutamine allows your muscles to fight and push a bit further, which boosts strength and it also has an important role in repairing the skeletal muscles.
A study found that L-glutamine supplementation makes it possible to recover quicker from intense weight sessions because it improves muscle hydration. This aids the muscle recovery process, along with a reduction in recovery time for wounds and burns.
Replenishing glutamine levels after an intense session could take up to five days, so it is important to take on a regular basis if you are doing intense exercise on a regular basis.
A study reported that glutamine also helps with human growth hormone secretion (HGH); this aids with fat metabolism and supports new muscle growth.
Research has indicated that HGH levels are up by nearly 400% after supplementing with L-glutamine; this hormonal response leads to an increase in resting metabolic rate and improves the after-burn effect or EPOC post exercise. This after-burn effect is essential for burning fat, weight loss and building lean muscle mass.
Other fat burning and lean muscle mass building benefits of supplementing with L-glutamine are that it can help to suppress insulin levels and stabilize blood glucose.
This enables the body to use up less muscle mass to maintain the blood sugars and insulin sensitivity in the cells. For this reason, L-glutamine benefits diabetics and those with sugar and carb cravings.